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Beetroot Extract Ameliorates DSS-Induced Colitis in Mice via Gut Microbiota Modulation

BiologicsOpen source preview, 2026, 6(1), 8

2026 Jurnal Internasional Scopus

Dwijayanti A., Kusmardi K., Fadilah F., Azizah N., Mohamad M.A.N.

Background: Dextran sodium sulfate (DSS)-induced colitis serves as a preclinical model for studying gut dysbiosis and inflammation relevant to inflammatory bowel disease (IBD) and its long-term complication of colorectal cancer (CRC). Beetroot (Beta ...

Lunasin‑Rich Soybean Extract Attenuates MMP‑9 Expression in an AOM/DSS Mouse Model of Colitis‑Associated Colorectal Cancer

Asian Pacific Journal of Cancer Biology

2026 Jurnal Internasional Scopus Vol. 11, No. 1

Muhammad Ikhsanul Azizi , Kusmardi Kusmardi

Background: Colorectal cancer (CRC) ranks as the third most common malignancy globally and is strongly associated with chronic inflammation, particularly colitis-associated cancer (CAC). Matrix metalloproteinase-9 (MMP-9) is a key enzyme in tumor inv...

6-gingerol as an antioxidant to ameliorate kidney injury in high-fat high-fructose diet-induced metabolic syndrome in rats

Journal of Applied Pharmaceutical Science Vol. 15(01), pp 072-080, January, 2025

2025 Jurnal Internasional Scopus

Vivian Soetikno1* , Andika Yusuf Ramadhan2 , Savira Wijaya3 , Diski Saisa3 , Syifa Nurfitriyanti3 ,Bryantlewi Santoso3, Kusmardi Kusmardi4, Shirly Gunawan5, Somasundaram Arumugam6,Remya Sreedhar7

Background and objectives: Diabetes mellitus (DM)-induced hypertrophic cardiomyopathy (HCM) isthe main reason for the high morbidity rate. 6-Gingerol has been shown to alleviate HCM by reducingoxidative stress and inflammation. The present study inve...

Effect of Vitamin C, Alpha Lipoic Acid (ALA), and Pentoxifylline on the Sperm Parameters, Cryosurvival Rate, and MDA Concentration after Thawing in Cryopreservation

International Journal of Technology, 2025, 16(1), pp. 348–358

2025 Jurnal Internasional Scopus

Luthfiana Hardianingtyas 1, Silvia W Lestari 2,*, Gita Pratama 3, Kusmardi Kusmardi4

Abstract: Cryopreservation provides available sperm for subsequent use in Assisted ReproductiveTechnology (ART), but it still has detrimental effects on sperm quality. Although severalinvestigations of the use of antioxidants in cryopreservation medi...

The Effect of Pomegranate Peel (Punica granatum L.) Extract in Chitosan Nanoparticle on the Macrophage Polarization in DSS-Induced Mice

Tropical Journal of Natural Product Research, 2025, 9(2), pp. 636–641

2025 Jurnal Internasional Scopus

Yogia Ikhsas1, Kusmardi Kusmardi2,3,4,*, Ria Kodariah2 , Fatiha Kamilah1

Macrophage polarization towards type 1 (M1) or type 2 (M2) is a critical determinant in re-establishing inflammation within the colon. Pomegranate is widely recognized as a biologicalsource for its substantial quantity and potent anti-inflammatory pr...

Oxidative Stress, DNA Fragmentation and Caspase-3 Regulation in HIV-1 Positive Men: A Study of Sperm Preparation

International Journal of Technology, 2025, 16(2), pp. 639–651

2025

Margaretha Napitupulu 1, Friska Zai 1, Silvia W Lestari 2,*, Latisha Witjaksono 3, Zulfikar Drakel 3,Dhriti Bhavnani 3, Evy Yunihastuti 4, Gita Pratama 5, Ria Kodariah 6, Kusmardi Kusmardi 6

Abstract: The impact of human immunodeficiency virus (HIV) infection on male fertility, specificallysperm quality, remains inconclusive in global studies. However, stable HIV-positive men undergoingantiretroviral therapy (ARV) experience improved qua...

Evaluating the effects of goat’s milk on inflammatory responses in rat model with gastritis

Malaysian Journal of Nutrition, 2025, 31(1), pp. 75–85

2025 Jurnal Internasional Scopus

Atun Farihatun1,2*, Kusmardi Kusmardi3,4,5*, Ari Estuningtyas6 & Mohd Nazil Salleh7

Introduction: Gastritis is a health issue that can lead to various complications,including chronic atrophic gastritis, gastric metaplasia/dysplasia, iron deficiencyanaemia, gastric bleeding, gastric perforation, and gastric cancer. Goat’s milkconta...

The potential role of goat milk in regulating CD4+ and CD8+ T cells in ethanol 80%-induced gastritis: A research using a gastritis rat model

Journal of Medicinal and Pharmaceutical Chemistry Research, 2025, 7(12), pp. 2809–2817

2025 Jurnal Internasional Scopus

Atun Farihatuna,b |Kusmardi Kusmardic,d,e,* |Ari Estuningtyasf |Moch. Nazil Sallehg

Gastritis, an inflammation in the stomach, is a result of severalfactors, including ethanol. In this investigation, rats were usedas models in order to examine how goat milk affects the ratio ofCD4+ and CD8+ immune cells in the stomachs of rats suffe...

Ficus deltoidea Ethanol Extract Cytotoxic Activity on MCF-7 Treated Doxorubicin: An In Silico and In vitro Approach

Tropical Journal of Natural Product Research, 2025, 9(5), pp. 1918–1923

2025

Rizky C Putri, Kusmardi, Rani W Hakim, Aditya E Nurfitrah

Female breast cancer is the most frequently diagnosed cancer worldwide, and the number of cases will increase in the next 20 years. Doxorubicin is an effective first-line chemotherapy for breast cancer. Unfortunately, continuous administration of dox...

The Effect of Pomegranate Peel (Punica granatum L.) Extract in Chitosan Nanoparticle on the Macrophage Polarization in DSS-Induced Mice

Tropical Journal of Natural Product Research

2025 Vol. 9, No. 2

Yogia Ikhsas, Kusmardi Kusmardi*, Ria Kodariah, Fatihah

Macrophage polarization towards type 1 (M1) or type 2 (M2) is a critical determinant in re-establishing inflammation within the colon. Pomegranate is widely recognized as a biological source for its substantial quantity and potent anti-inflammatory p...